Amikacin pharmacokineticpharmacodynamic analysis in pediatric. Amikacin is used for short term treatment of serious infections caused by. It is desirable to limit the duration of treatment to short term whenever feasible. Following administration of the last dose of the repeateddose regimen, amikacin continued to be excreted slowly into the urine fig. Amikacin is a semisynthetic aminoglycoside antibiotic derived from kanamycin. Go to the output file format as following, choose doc. Product monograph pr amikacin sulfate injection usp 250 mgml amikacin antibiotic sandoz canada inc. Administer arikayce with the lamira nebulizer system only. Identify patient select site prepare injection a draw the amikacin into the 5 ml syringe using the 1inch 22 or 23 gauge needle.
Amikacin sulphate is an aminoglycoside antibiotic with. Do not selfinject this medicine if you do not understand how to give the injection and. Jan 08, 2020 arikayce also known as liposomal amikacin for inhalation, or lai is an approved treatment for adults developed by insmed to treat lung infections caused by mycobacterium avium complex mac, a type of nontuberculous mycobacteria ntm, which have not responded to standard treatments. It may also be given into a vein, either as an injection or following dilution as an infusion drip. To help clear up your infection completely, keep using this medicine for the full time of treatment, even if you begin to feel better after a few days. Solumedrol methylprednisolone sodium succinate for. It contains the equivalent of not less than 674 mcg and not more than 786 mcg amikacin per mg, calculated on the dried basis. If victim is not breathing, clear airway and immediately begin artificial respiration. Insert pdf into word on mac its easy to insert pdf into word on a mac device as well. Amikacin sulfate amikin discontinued is an antibiotic injection prescribed to treat bacterial meningitis, infected burns, cystic fibrosis, and severe uti infections.
Similar to other aminoglycosides, it works by inhibiting bacterial protein synthesis through irreversible binding to the 30 s ribosomal subunit of susceptible bacteria. Click convert to make the pdf in word format on windows. Nov 16, 2011 common commercial concentrations of amikacin are 50 mgml and 250 mgml. It is also used for the treatment of multidrugresistant tuberculosis. Amikacin s structure has been altered to reduce enzymatic deactivation, thus reducing bacterial resistance. Product identification product name amikacin sulfate injection, usp product use broad spectrum antibiotic manufacturer teva parenteral medicines, inc.
Amikacin injection is a semisynthetic, aminoglycoside antibiotic which is. Current dosing guidelines for amikacin in neonates are based on weight andor age descriptors. Amikacin sulfate injection, usp sagent pharmaceuticals. Inserting pdf document into a word document microsoft. The object dialog box will appear select create from file. Pdf in vitro efficiency of amikacin inhale, a novel drugdevice. To reduce the development of drugresistant bacteria and maintain the effectiveness of the amikacin and other antibacterial drugs, amikacin should be used only to treat or prevent infections that are proven or strongly suspected to be caused by bacteria. In patients with impaired renal function, either the dose or the dosage interval. Amikacin dosing, indications, interactions, adverse. Percocetoxycodone and acetaminophen tablets, uspcii rx.
Inhaled amikacin for treatment of refractory pulmonary. It is usually given every 8 hours or as directed by your doctor. Information on submitting spl files using elist may be found in the guidance for industry titled spl standard for content of labeling technical qs and as at. Amikacin 250 mg injection is used to treat a variety of bacterial infections of the lungs, skin, abdomen, and blood caused by li, streptococci, enterococci, etc. Percocet oxycodone and acetaminophen tablets, usp is supplied as follows. Amikacin should not be physically premixed with other drugs but should be administered separately according to the recommended dose and route. Evaluating renal function and age as predictors of amikacin. Amikacin can also be given into the peritoneum abdominal cavity during surgery, and can be used to wash out abscess cavities, the lung cavity and. Pdf on mar 1, 20, n kadrichu and others published in vitro efficiency of amikacin inhale, a novel. Embed pdf in word embed a pdf document into microsoft word.
Pharmacokinetics and urinary excretion of amikacin in low. Prior to opening, shake the arikayce vial well for at least 10 to 15 seconds until the contents appear uniform and well mixed. Dec 02, 2019 amikacin is injected into a muscle, or into a vein through an iv. Open the word file, the file originally saved in pdf is inserted into the word document successfully. This medication is given by injection into a vein or muscle as directed by your doctor. Urine should be examined for decreased specific gravity, increased excretion of proteins, and the presence of cells or casts. We evaluated the effectiveness and toxicity of inhaled amikacin in 20 patients with treatmentrefractory nontuberculous mycobacterial lung disease. In the text group click the dropdown arrow for object and select object. Amikacin is used to treat severe or serious bacterial infections. In the ifu tab you can either use the product code search or the keyword search. Only use the type of nebulizer that you have been told to use.
Each 2 ml vial contains amikacin sulfate equivalent to amikacin activity 500 mg 500,000 i. Ndc 0641616610 rx only amikacin sulfate injection, usp equivalent to amikacin 1 gram4 ml 250 mgml for intramuscular or intravenous use 10 x 4 ml vials each ml contains 250 mg amikacin as sulfate, 0. Hence, it should be used with extreme caution in elderly patients as well as. This includes joint infections, intraabdominal infections, meningitis, pneumonia, sepsis, and urinary tract infections. However, there is minimal literature pertaining to the efficacy of and side effects associated with inhaled amikacin. Many gram negative organisms resistant to gentamicin and tobramycin in vitro are sensitive to amikacin. Amikacin is actively transported into the bacterial cell where it binds to receptors present on the 30 s ribosomal subunit. Amikacin injection manufacturers, suppliers and exporters. In vitro studies have shown that amikacin sulfate combined with a betalactam antibiotic acts synergistically against many clinically signi.
The verification of your account may take up to 5 business days. Amikacin is an antibiotic used for a number of bacterial infections. The file location will now appear on the object dialog box. So far, when i insert the pdf, i only get a link to click on. The measurements obtained are used in the diagnosis and treatment of amikacin overdose and in monitoring levels of amikacin to ensure appropriate therapy.
Go to the insert tab and go to the option of object. The product catalog provides you with a full listing of tevas brand and generic product lines. Amikacin may be administered once or twice a day and is usually given by the intravenous or intramuscular route, though it can be given via nebulization. Considering the higher maximum and lower minimum levels of amikacin in the neonates receiving the daily dosage regimen. Word offers many features that help you present a wide range of different documents, and some can be confusing if youre unfamiliar with them. Amikacin should not be physically premixed with other drugs but should be administered separately according to the recommended dosage and route. Careful recordkeeping of prescribing information, including quantity, frequency, and renewal requests, as required by state and federal law, is strongly advised. Intended use the qms amikacin assay is intended for the quantitative determination of amikacin in human serum or plasma on automated clinical chemistry analyzers. Amikacin dosage dosage for serious bacterial infections adult adults and children over 12 years recommended. Amikacin 250 mg injection uses, dosage, side effects. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment.
Vials containing a clear, colourless to pale yellow solution. Open the word document and select insert on the ribbon. The catalog displays all strengths and sizes along with the description, imprint code, ndc and photo for each product. Inserting pdf document into a word document i want to insert a pdf file into a word document and then be able to print the entire document. Click on the object button, and a dialog box will open. When you click on object, youll get a dialog box, and here you will want to click on the create from file tab. These amikacin injection manufacturing companies are offering high quality products to the clients on time. Do not selfinject this medicine if you do not understand how to give the injection and properly dispose of used needles, iv tubing, and other items used to inject the medicine.
Over time, as amikacin pkpd became better understood, dosing changed to larger oncedaily doses in order to. If stored in a refrigerator, let this drug come to. Important headings, with respect to its pharmacology, along with a note on important dosage regimen. Amikacin definition, a widespectrum semisynthetic antibiotic, c22h45n5o, used in the treatment of infections, especially those caused by susceptible gramnegative bacilli. For outlook, click inside of the body of an item, such as an email message or calendar event. Amikacin sulfate is stable for 24 hours at room temperature at concentrations of 0. Hazard statements aminoglycosides may cause potential ototoxicity and nephrotoxicity, as well as fetal harm, allergictype reactions, and associate diarrhea. Indications 1, 2 amikacin must be reserved for treating infections due to microorganisms that are resistant to other aminoglycosides. Amikacin is a semisynthetic aminoglycoside antibiotic used in the treatment of gramnegative infections resistant to gentamicin. Amikacin sulfate injection, usp, 250 mgml, is supplied as follows. Methylprednisolone sodium succinate, usp, is the sodium succinate ester of methylprednisolone, and it occurs as a white, or nearly white, odorless hygroscopic, amorphous solid.
How to insert a pdf file into a word document online tech tips. Pronunciation of amikacin with 1 audio pronunciation, 10 translations, 2 sentences and more for amikacin. If you dont receive any notification please use our online contact form for technical documents or send an email to us. Amikacin medical definition merriamwebster medical dictionary. Amikacin investigated as a drug, natural product, and reproductive effector.
You can also import a portion of text from the pdf file using the insert object tool, and drop it into the word document. Amikacin 674786gmgasamikacinbase 39831555 sigmaaldrich. Arikayce consists of liposomes that contain amikacin, an antibiotic. Find patient medical information for amikacin injection on webmd including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Amikacin intended use the tdxtdxflx amikacin assay is a reagent system for the quantitative measurement of amikacin, an aminoglycoside antibiotic drug, in serum or plasma.
This word document deals with the drug profile of amikacin. Amikacin fda prescribing information, side effects and uses. Dec 06, 2019 aminocaproic acid injection, usp, for intravenous administration, is a sterile pyrogenfree solution containing 250 mgml of aminocaproic acid with benzyl alcohol 0. The steps are relatively similar to insert a pdf into word using a mac, but there may be some title differences.
Amikacin is injected into a muscle, or into a vein through an iv. Amikacin sulphate 500 mg injection uses, dosage, side. Only select registry of toxic effects of chemical substances rtecs data is presented here. At times the solution may become pale yellow in color. Hence, it should be used with extreme caution in elderly patients as well as in patients with kidney diseases. Amikacin sulphate 500 mg injection is used to treat a variety of bacterial infections of the lungs, skin, abdomen, and blood caused by li, streptococci, enterococci, etc. When amikacin is indicated in newborns see boxed warnings, it is recommended that a loading dose of 10 mgkg be administered initially to be followed with 7. Holding the syringe in an up right position, change. The use of aerosolized amikacin has the potential for reduced toxicity.
Serum concentrations of amikacin should be monitored when feasible to assure adequate levels and to avoid potentially toxic levels and prolonged peak concentrations above 35 micrograms per ml. For reagent ifus instructions for usepackage insert sheets please select the tab ifu. Dec 17, 2018 amikacin sulfate injection, usp is supplied as a colorless solution which requires no refrigeration. Nov 09, 2018 amikacin is injected into a muscle, or into a vein through an iv. One of these is the insert pdf to word tool, which enables you to insert a pdf file into a word document in its entirety, or by attaching it as a clickable object. The steps below apply to word 2010, 20, 2016, 2019, and word for office 365. If respiratory symptoms develop, move victim away from source of exposure and into fresh air. Amikacin should not be physically premixed with other drugs, but should be administered separately according to the recommended dose and route. Webmd provides common contraindications for amikacin injection. There is no oral form available, as amikacin is not absorbed. Amikacin photo key points amikacin is an aminoglycoside antibiotic that inhibits bacterial growth in susceptible organisms by interfering with bacterial protein synthesis binds to 30s and 50s ribosomal subunits, resulting in a defective bacterial cell membrane exhibit concentrationdependent bacterial killing higher peak levels means more bacterial killing has activity against many. For example, to insert a pdf into word using a mac, instead of selecting create from file and browse as you would on windows after selecting insert object, you would simply select. Amikacin sulfate injection, uspfor intramuscular or.
Find out what health conditions may be a health risk when taken with amikacin injection. Data sources include ibm watson micromedex updated 10 apr 2020, cerner multum updated 6 apr. Product code search allows you to enter the product code into the field ref, the lot number in the field lot, and the revision information in the third box if. Amikacin sulphate injection may be given intramuscularly or intravenously.
This medicine is given as a shot into a muscle or into a vein. Find here directory of amikin injection manufacturers, amikacin injection suppliers and exporters. Run and import pdf files into the program by clicking add pdf. Amikacin dosing, indications, interactions, adverse effects. When amikacin is injected intravenously, it is usually infused injected slowly over a period of 30 to 60 minutes. Federal law restricts this drug to use by or on the order of a licensed veterinarian.
Please reference package insert for additional information. At times the solution may become a very pale yellow. Amikacin injection comes as a liquid to be injected intravenously into a vein or intramuscularly into a muscle every 8 or 12 hours two or three times a day. Reliability of assay results cannot be guaranteed if there are any deviations from the instructions in this package insert. See actual entry in rtecs for complete information. Hence, it should be used with extreme caution in elderly patients as well as in patients with kidney. Amikacin can also be given into the peritoneum abdominal cavity during surgery, and can be used to wash out abscess cavities, the lung cavity and brain cavities. Amikacin sulphate is an aminoglycoside antibiotic with activity against a broad spectrum of gramnegative organisms such as pseudomonas species, escherichia coli, klebsiellaenterobacterserratia and salmonella species author. Qualitative and quantitative composition amikacin is a semisynthetic aminoglycoside antibiotic derived from kanamycin. However, this will only insert the text without the original formatting or graphics if any from the pdf file, so it wont look. Amikacin is not absorbed orally and is given by either intramuscular or slow intravenous injection either once or twice daily or, in severe infections, three times daily. Arikayce also known as liposomal amikacin for inhalation, or lai is an approved treatment for adults developed by insmed to treat lung infections caused by mycobacterium avium complex mac, a type of nontuberculous mycobacteria ntm, which have not responded to standard treatments. This medicine is known to cause serious kidney problems and hearing problems, especially in the elderly population. Package insert instructions must be followed accordingly.
Dosage of amikacin sulfate is expressed in terms of amikacin and calculated on a. If you are using mac to insert a pdf file into word, the method is mostly the same. Amikacin sulfate amikacin sulfate dose, indications. Amikacin may be combined with a betalactam antibiotic for empiric therapy for people with neutropenia and fever. Oct, 2015 the mean sd mcs predicted c max and auc 24 values and cfr are provided in table 2 and centered on tbwbased and dwbased doses and a fixed dosing approach. You can follow the question or vote as helpful, but you cannot reply to this thread.
Click insert to insert the images into the word document. Apr 01, 2019 amikacin should not be physically premixed with other drugs but should be administered separately according to the recommended dose and route. Once the pop up appears, go to the from file button at the bottom. Pdf standard multiple and single daily dosing of amikacin in. It acts by inhibiting protein synthesis of susceptible bacteria. Percocet, like other opioids, can be diverted for non medical use into illicit channels of distribution. With word 2007 in the xp operating system it was easy, i just clicked and draged pdf the document into the word document. Ndc 0641616710, 2 ml single dose vial packaged in a carton of 10. If you are not sure what type of nebulizer to use, talk with the doctor. Broad spectrum antibiotic amikacin sulfate injection, usp.
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